| 발표일자: |
2013년 11월 1일(금) ~ 11월 3일(일) |
| 발표번호: |
P(e-poster)-011 |
| 발표장소: |
킨텍스 제2전시장 7B홀 |
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| 정상안압녹내장 환자에서 전신적 MMP-9의 농도와 손톱주름 모세혈관 현미경 검사 결과의 상관관계 |
| 가톨릭대학교 의과대학 안과학교실, 인천성모병원¹, 서울성모병원² |
| 이나영, 유별, 한재욱, 오승훈, 강규동, 임혜빈, 박찬기 |
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목적 : To investigate the association of the plasma levels of matrix metalloproteinase-9 (MMP-9) and nailfold capillaroscopy, heart rate variability, optic disc hemorrhage, visual field progression in normal tension glaucoma patients.
방법 : Twenty-five patients with NTG were enrolled in this study. Subjects with systemic diseases were excluded. All patients underwent a complete ophthalmic examination and were referred to the rheumatology department, where nailfold capillaroscopy and HRV assessment were performed. Blood samples from all subjects were assayed for MMP-9 concentrations.
결과 : The systemic levels of MMP-9 was significantly associated with the result of nailfold capillaroscopy (ρ = 0.439, p = 0.032). However, there were no significant association with HRV parameters, disc hemorrhage, progression of VF and the levels of systemic MMP-9 levels.
결론 : Systemic MMP-9 levels were associated with the results of nailfold capillaroscopy, whereas HRV parameters, local disc hemorrhage, and progression of glaucomatous visual field.
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