| 발표일자: |
2013년 11월 1일(금) ~ 11월 3일(일) |
| 발표번호: |
P(e-poster)-002 |
| 발표장소: |
킨텍스 제2전시장 7B홀 |
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| 일차성 개방각 녹내장 환자에서 발생한 시신경 유두출혈의 지형학적 특성 |
| ¹ 서울대학교 의과대학 안과학교실
² 서울대학교 의생명공학과 |
| 김영국(1), 박기호(1), 유병욱(2), 김희찬(2), 정진욱(1), 김동명(1) |
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목적 : To investigate the topographic characteristics of optic disc hemorrhage (DH) and the factors associated with DH area in primary open-angle glaucoma (POAG).
방법 : One hundred and twenty-eight POAG eyes (with DH) of 128 patients were included consecutively. Digital red-free retinal nerve fiber layer photographs (RNFLPs) of the enrolled eyes were reviewed and the DH location was measured. The DH area/disc area ratio was calculated based on retinal nerve fiber layer deviation map/RNFLP overlay image; mean values were used in cases where DH recurred more than once in the same eye. The DH area was computed by multiplication of the DH area/disc area ratio by the optic disc area measurement from Cirrus spectral-domain optical coherence tomography (SD-OCT).
결과 : DHs were most common in the inferotemporal inferior sector (58.0%) and the disc rim (40.6%) in terms of octant and proximal location, respectively. In a multivariate analysis, a larger DH area was associated with older age (P<0.001), use of acetylsalicylic acid (P = 0.027), lower baseline intraocular pressure (IOP) (P = 0.007), and lower cup-to-disc ratio (P<0.001). In normal-baseline-IOP POAG eyes (n = 88), overall DH area and the length of maximum radial extent of DH were larger than in high-baseline-IOP POAG eyes (n = 40) (P = 0.039 and 0.028, respectively).
결론 : In POAG eyes, DH was larger in area and longer in length in normal-baseline-IOP than in high-baseline-IOP. This suggests the possibility that previous studies’ findings of higher DH prevalence and incidence in normal-baseline-IOP POAG eyes were affected by these topographic characteristics, which make DH to be more easily detected.
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