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목적 : To evaluate the long-term clinical outcomes in primary congenital glaucoma (PCG) patients in South Korea.
방법 : Medical records of PCG patients from seven hospitals in South Korea were examined. Success rate was analyzed with Kaplan-Meier method for clustered data. Final prognosis were categorized according to World Health Organization classification and IOP control status:Group 1 : IOP well controlled, no visual impairment (20/20) ; Group 2 : IOP well controlled, low vision (0.3-1.0) ; Group 3 : IOP well controlled, lower vision (0.05-0.3) ; Group 4 : WHO legally blindness ; Group 5: uncontrolled IOP, demands treatment. The associations of prognosis and various factors were analyzed using mixed model.
결과 : In total 154 eyes, mean follow up period was 137.8 months. The probability of second operation was 29.4 % at postoperative one year, 38.2% after five years passed. Failure slope became stable since ten years passed. In final prognosis, 33.7% of PCG patients were included in group 1, 21.3 % in group 2 and 21.3 % in group 3. 19.1% had finally blindness in one eye or both eyes. The numbers of surgical interventions was weakly, but positively correlated with poorer prognosis (Spearman correlation coefficient = 0.31154, P-value = 0.004). 20.9% patients have amblyopia and 13.9% had strabismus.
결론 : The probability of second operation after first intervention was continuously increased for a follow up period. In final prognosis, over half of PCG patients had visual impairment. Asides from IOP, the close monitoring about visual acuity and ocular morbidities is carefully needed.
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