| 발표일자: |
2013년 11월 1일(금) ~ 11월 3일(일) |
| 발표번호: |
P(판넬)-002 |
| 발표장소: |
킨텍스 제2전시장 7B홀 |
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| 개방각 녹내장 환자에서 24시간 활동혈압 매개변수에 대한 해석 ; 혈압의 변동성 (선행연구) |
| 1 차의과학대학교 분당차병원 안과학교실
2 차의과학대학교 분당차병원 심장내과학교실
3 연세대학교 의과대학 안과학교실 시과학연구소 |
| 노승수1, 문재연2, 성영제1, 유혜린1, 김찬윤3 |
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목적 : It has been more than 10 years since blood pressure (BP) variability has been related to target organ damage. We designed this study to figure out the impacts of 24 hour ambulatory blood pressure variability (BPV) in the different severity of glaucomatous damage.
방법 : We performed 24 hour ambulatory blood pressure monitoring (ABPM) in 34 eyes of 34 open-angle glaucoma patients. BPV was calculated as nocturnal dip (ND), morning BP surge (MBPS), the standard deviation(SD) of BP, and weighted fashion SD (wSD). These BPV parameters were compared between early damage group (n=16) and moderate to severe damage group (n=18), and they also compared between age-matched early damage group (n=10) and severe damage group (n=10).
결과 : In comparison of early damage and moderate to severe damage group, ND and MBPS were not significantly different (Fisher’s exact test), however the SD of daytime BP (p=0.001) and the wSD of fulltime BP (p=0.003) were higher in moderate to severe damage group with statistical significance (Mann-Whitney test). After age-matching, the ratios of ND and MBPS, the SD of daytime BP and the wSD of fulltime BP were higher with statistical significance.
결론 : This is a pilot study result implicating that 24 hour ambulatory BPV is related to the severity of glaucomatous damage. Hence a larger scale study is needed in the future.
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