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목적 : To evaluate the pattern and progression of retinal vasculitis in Behçet patients using the fluorescein angiography (FA) scoring system.
방법 : This retrospective, observation study included a total 74 eyes of 45 patients who completed at least 2 years of follow-up. FA was taken during the periods of retinal vasculitis and the quiescent phase, and was analyzed using a FA scoring system. Nine categories were evaluated: optic disc hyperfluorescence, macular edema, retinal vascular staining/leakage, capillary leakage, capillary nonperfusion, neovascularization of optic disc and elsewhere respectively, pinpoint leakage, and subretinal pooling. The total maximum FA score for each eye was 40.
결과 : During 53.61±20.65 months, mean 2.67 ± 1.66 times of acute exacerbations were noted after the first attack of retinal vasculitis. Mean total scores were 15.43±6.78 at the first attack, and 15.25±7.43 at the first exacerbation (P=.890). Mean total scores of each acute exacerbation were not significantly different from those of the first attack (P =.940 at second, and P =.910 at third). Mean total scores were 9.96±5.03 at quiescent phase, significantly lower than those of active phase (P =.018 at the first attack, P =.015 at first, P=.018 at second, and P=.020 at third).
결론 : Retinal vasculitis of Behçet disease had similar patterns when exacerbated, and did not significantly progress when treated properly. Although the mean total FA scores and the mean scores of each angiographic sign were not significantly correlated with visual outcome, the inflammatory activity of retinal vasculitis was well documented by the FA scoring system. Angiographic signs of vascular leakage reflected inflammatory activity of retinal vasculitis, and should be monitored carefully to detect acute exacerbations, so that proper treatment may prevent further visual loss in these patients.
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