대한안과학회 제109회 학술대회 발표 연제 초록
 
발표일자: 2013년 04월 21일 (일)
발표시간: 15:34~15:42
발표번호: 망막F-066
발표장소: B방
Treatment outcome of intra-arterial thrombolysis for central retinal artery occlusion
서울대학교 의과대학 안과학교실 (1), 분당서울대학교병원 안과(2), 영상의학과 (3), 신경과 (4)
우세준 (1,2), 안성준 (1,2), 김재민 (1), 안지윤 (1), 박규형 (1,2), 정철규 (3), 한문구 (4)
목적 : To investigate treatment outcomes of intra-arterial thrombolysis (IAT) for acute non-arteritic central retinal artery occlusion (CRAO) and perform subgroup analyses according to CRAO stage.방법 : For 101 patients with acute non-arteritic CRAO including 57 and 44 patients in the IAT and conservative treatment (CT) groups, a retrospective review of medical records was performed. CRAO was categorized as incomplete and complete CRAO based on funduscopic and angiographic findings. Between the IAT and CT groups, the final best-corrected visual acuity (BCVA) and early (≤3 days) and final (1 month) reperfusion (improvement of retinal perfusion) rate on fluorescein angiography were compared. 결과 : Overall visual outcomes did not significantly differ between groups, whereas early reperfusion was greater in the IAT group (73.1% vs. 42.3%, P = 0.013). In incomplete CRAO, the IAT group showed greater visual improvement (1.09 ± 0.48 vs. 0.27 ± 0.53 logarithmic minimum angle of resolution [logMAR], P = 0.011). In complete CRAO, there were no significant differences in visual outcomes between the 2 groups.결론 : IAT is helpful for early restoration of retinal perfusion in CRAO. However, this procedure may be functionally beneficial only for incomplete CRAO in the usual clinical setting.