| 대한안과학회 제109회 학술대회 발표 연제 초록 |
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| Ultraviolet-visible light spectral transmittance of rabbit corneas after Riboflavin / ultraviolet- A (365 nm) corneal collagen cross-linking |
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| 한림대학교 의과대학 안과학교실(1), 가톨릭대학교 의과대학 안과학교실(2) | |||||||||
| 황호식(1), 김만수(2) | |||||||||
| 목적 : To determine the effect of riboflavin /ultraviolet-A (365nm) corneal collagen cross-linking on transmission of the ultraviolet-visible (UV-VIS) light spectrum through the cornea방법 : Twelve New Zealand white male rabbits were used in this research. Cross-linking was performed unilaterally on the animal’s right eye, whereas only epithelial removal was done on the left, as a control. Seven weeks after cross-linking, the animals were euthanized and the enucleated eyes were processed for transmission spectroscopy. To confirm that the cross-linking procedures were performed correctly on the right corneas, the tensile force-extension relationship was measured using six corneas from three of the rabbits after undergoing transmission spectrum determination결과 : Seven weeks after cross-linking, 10 of 12 rabbits exhibited clear corneas in both the cross-linked and control eyes. In control corneas, transmittance was 95.95% at 650 nm, and decreased continuously as the wavelength decreased. Below 315 nm, the transmittance rapidly decreased, to 40.29% at 300 nm. The transmittance of cross-linking corneas was 10–20% lower than that of control corneas. The difference was 8.383% at 650 nm and increased as the wavelength shortened, reaching a maximum of 20.591% at 320 nm, and decreased rapidly to 4.770% at 300 nm.결론 : The transmittance of cross-linked corneas was 10–20 % lower than that of control corneas. The difference increased with decreasing wavelength, reaching a maximum at 320 nm and then decreasing rapidly. UV collagen cross-linking showed a protective effect against ultraviolet penetration. |
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