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목적 : To evaluate frequency and rate of progression of regional visual field (VF) loss in patients with early open angle glaucoma (OAG) undergoing the event-based VF progression assessed by Humphrey VF analyzer
방법 : Full threshold central 24-2 VF data were obtained from early OAG patients with VF progression and a minimum of 4 tests over at least 2 years. After adjusting age, sex, laterality, spherical equivalent, baseline/mean intraocular pressure, baseline VF global indices, generalized estimate equation was analyzed with respect to mean thresholds of regional clusters in central 10 and peripheral 10 to 24 degrees (superior and inferior hemi-fields), and clusters of VF division according to Garway-Heath map. VF Progression was defined as the negative slope with statistical significance (p < 0.05).
결과 : 52 eyes of 45 patients with a mean follow-up period of 6.2 years (2.1 to 10.2) and a mean number of VF tests of 6.3 (4 to 13) were included. In VF map composed of central 10 and peripheral 10 to 24 degrees, most frequent and fastest region in progression was the superior central area (35.5%, -0.26 dB/year). In Garway-Heath map, VF region corresponding to inferotemporal sector of optic nerve head (271 to 310 degrees) showed the most frequent and fastest (30.1%, -0.27 dB/year) progression.
결론 : In patients with early OAG, trend-based VF progression was less than event-based progression, and the regional parameter, especially central area in superior hemi-field could be more useful than any other regions in terms of detecting the VF progression.
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